We have limited openings for motivated, spirited graduate students, postdoctoral fellows, and undergraduates.


Interested?

If you are interested in joining the lab, please send an email to Will, and include your CV and a brief statement of why you are interested in our work. We look forward to hearing from you!


Postdoctoral Position Available: Analysis of epigenomic data sets from cancer genome atlas

The Greenleaf lab is looking to recruit a postdoctoral fellow interested in analysis of large data sets generated from open chromatin assays carried out in tissues from the cancer genome atlas. An ideal candidate would have a Ph.D. in Cancer Biology, Biochemistry, Biology, Immunology, Biophysics, Physics, Biomedical Informatics, Genome Sciences, Computer Science, Mathematics, or a related field, and have experience with high-throughput sequencing data. Experience with DNase-seq or FAIRE-seq data would be ideal. Please send a CV, including the names of 3 references, along with a letter describing your previous experience and current interests to Will Greenleaf.


Postdoctoral Position Available: High-throughput investigations of the epigenetic basis of gene regulation

The Greenleaf lab is looking to recruit a postdoctoral fellow interested in using Cas9/CRISPR screens to perturb regulatory elements in a high throughput manner, then use genomic methods for probing the epigenome and transcriptome to quantify these perturbations. Our ultimate goal is a predictive model of the relationship between regulatory element activity and gene expression output.An ideal candidate would have a Ph.D. in Molecular Biology, Biochemistry, Biology, Immunology, Biophysics, Physics, Biomedical Informatics, Genome Sciences, Computer Science, Mathematics, or a related field, and have experience with high-throughput sequencing data. Experience with DNase-seq or FAIRE-seq data would be ideal. Please send a CV, including the names of 3 references, along with a letter describing your previous experience and current interests to Will Greenleaf.


Postdoctoral Position Available: Analysis of chromatin secondary structure

The Greenleaf lab is looking to recruit a postdoctoral fellow interested in using correlated cleavage mapping of DNA (RICC-seq) to understand the secondary structure of chromatin in multiple model organisms. An ideal candidate would have a Ph.D. in Molecular Biology, Biochemistry, Biology, Immunology, Biophysics, Physics, Biomedical Informatics, Genome Sciences, Computer Science, Mathematics, or a related field, and have experience with high-throughput sequencing data. Experience with molecular modeling would be ideal. Please send a CV, including the names of 3 references, along with a letter describing your previous experience and current interests to Will Greenleaf.


Postdoctoral Position Available: Integrative chromatin analysis tools

The Greenleaf lab is looking to recruit a postdoctoral fellow interested in the design and implementation of comprehensive data analysis methods to integrate multi-modal, time series genomic data sets to provide causal links between regulatory changes (in chromatin) and gene expression changes, both in bulk and single cell data sets. An ideal candidate would have a Ph.D. in Biophysics, Physics, Biomedical Informatics, Genome Sciences, Computer Science, Mathematics, or a related field, and have experience with high-throughput sequencing data. Experience with machine learning methods would be a plus. Please send a CV, including the names of 3 references, along with a letter describing your previous experience and current interests to Will Greenleaf.


Postdoctoral Position Available: Stem Cells

The Greenleaf lab is looking to recruit a postdoctoral fellow interested in examining variations of the regulatory landscape of single iPS and ES cells. We have developed a single-cell platform for analyzing variations in regulatory elements, and are funded to link changes in gene expression observed during skin differentiation at the single cell level to molecular drivers of these phenotypic changes. In the long run, our goal is to link causal variation in enhancers, promoters, and insulators to downstream changes in gene expression patterns. An ideal candidate would have a Ph.D. in Molecular Biology, Biochemistry, Biology, Immunology, Biophysics, Physics, Biomedical Informatics, Genome Sciences, Computer Science, Mathematics, or a related field, and have experience with high-throughput sequencing data. Experience with DNase-seq or FAIRE-seq data would be ideal. Please send a CV, including the names of 3 references, along with a letter describing your previous experience and current interests to Will Greenleaf.


Postdoctoral Position Available: Immunity

The Greenleaf lab is looking to recruit a postdoctoral fellow interested in examining variations of the regulatory landscape of single immune cells. We have developed a single-cell platform for analyzing variations in regulatory elements, and are funded to link changes in gene expression observed at the single cell level to molecular drivers of these phenotypic changes. In the long run, our goal is to link causal variation in enhancers, promoters, and insulators to downstream changes in gene expression patterns. An ideal candidate would have a Ph.D. in Molecular Biology, Biochemistry, Biology, Immunology, Biophysics, Physics, Biomedical Informatics, Genome Sciences, Computer Science, Mathematics, or a related field, and have experience with high-throughput sequencing data. Experience with DNase-seq or FAIRE-seq data would be ideal. Please send a CV, including the names of 3 references, along with a letter describing your previous experience and current interests to Will Greenleaf.


Postdoctoral Position Available: Tech. Development

The Greenleaf lab is looking to recruit a postdoctoral fellow interested in developing novel transposase-based platforms for fast and sensitive epigenetic analysis. We are developing methods for assaying chromatin looping interactions, as well as methods that rely on affinity directed transposition of sequencing tags for multiplex measurements of DNA-protein interactions, such as transcription factor binding as well as post translationally modified nucleosomes. This project is well-funded, and we have already produced exciting preliminary data sets. An ideal candidate would have a Ph.D. in Molecular Biology, Biochemistry, Biology, Immunology, Biophysics, Physics, Biomedical Informatics, Genome Sciences, Computer Science, Mathematics, or a related field, and have experience with high-throughput sequencing data. Experience with DNase-seq or FAIRE-seq data would be ideal. Please send a CV, including the names of 3 references, along with a letter describing your previous experience and current interests to Will Greenleaf.